KeyboardEvent.getModifierState()

var active = event.getModifierState(keyArg);

// Ignore if following modifier is active.
if (event.getModifierState("Fn") ||
    event.getModifierState("Hyper") ||
    event.getModifierState("OS") ||
    event.getModifierState("Super") ||
    event.getModifierState("Win") /* hack for IE */) {
  return;
}

// Also ignore if two or more modifiers except Shift are active.
if (event.getModifierState("Control") +
    event.getModifierState("Alt") +
    event.getModifierState("Meta") > 1) {
  return;
}

// Handle shortcut key with standard modifier
if (event.getModifierState("Accel")) {
  switch (event.key.toLowerCase()) {
    case "c":
      if (event.getModifierState("Shift")) {
        // Handle Accel + Shift + C
        event.preventDefault(); // consume the key event
      }
      break;
    case "k":
      if (!event.getModifierState("Shift")) {
        // Handle Accel + K
        event.preventDefault(); // consume the key event
      }
      break;
  }
  return;
}

// Do something different for arrow keys if ScrollLock is locked.
if ((event.getModifierState("ScrollLock") ||
       event.getModifierState("Scroll") /* hack for IE */) &&
    !event.getModifierState("Control") &&
    !event.getModifierState("Alt") &&
    !event.getModifierState("Meta")) {
  switch (event.key) {
    case "ArrowDown":
    case "Down": // hack for IE and old Gecko
      event.preventDefault(); // consume the key event
      break;
    case "ArrowLeft":
    case "Left": // hack for IE and old Gecko
      // Do something different if ScrollLock is locked.
      event.preventDefault(); // consume the key event
      break;
    case "ArrowRight":
    case "Right": // hack for IE and old Gecko
      // Do something different if ScrollLock is locked.
      event.preventDefault(); // consume the key event
      break;
    case "ArrowUp":
    case "Up": // hack for IE and old Gecko
      // Do something different if ScrollLock is locked.
      event.preventDefault(); // consume the key event
      break;
  }
}